Publications (CEC Faculty in bold)

2014
  • Using Systems Biology to Understand Cancer as an Evolutionary Process. John W. Pepper, Barbara K. Dunn, Richard M. Fagerstrom, John K. Gohagan, and Nadarajen A. Vydelingum. Journal of Evolutionary Medicine
    Vol. 2 (2014), Article ID 235678
  • The evolution of cancer-related genes in hominoids. Kang, Ling and Michalak Pawel. 2015. J Mol Evol 80:37-41
  • Stochastic modeling indicates that aging and somatic evolution in the hematopoietic system are driven by non‐cell‐autonomous processes. Andrii I. Rozhok, Jennifer L. Salstrom and James DeGregori. AGING, December 2014, Vol 6, N 12
  • Microenvironmental acidosis in carcinogenesis and metastases: new strategies in prevention and therapy. Fais, Stefano; Venturi, Giulietta; Gatenby, Bob.  CANCER AND METASTASIS REVIEWS 33(4): 1095-1108. Special Issue: SI
  • Complex metastatic niches: already a target for therapy? Ordonez-Moran, Paloma; Huelsken, Joerg. CURRENT OPINION IN CELL BIOLOGY
    Volume: 31; Pages: 29-38
  • MET, a driver of invasive growth and cancer clonal evolution under therapeutic pressure. Boccaccio, Carla; Comoglio, Paolo M. CURRENT OPINION IN CELL BIOLOGY  Volume: 31   Pages: 98-105
  • Timing and heterogeneity of mutations associated with drug resistance in metastatic cancers. Bozic, Ivana; Nowak, Martin A. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA  Volume: 111   Issue: 45   Pages: 15964-15968
  • Attack of the clones. Govindan, Ramaswamy. SCIENCE  Volume: 346   Issue: 6206   Pages: 169-170
  • Spatial and temporal diversity in genomic instability processes defines lung cancer evolution. de Bruin, Elza C.; McGranahan, Nicholas; Mitter, Richard; et al. SCIENCE  Volume: 346   Issue: 6206   Pages: 251-256
  • Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity. Marusyk, Andriy; Tabassum, Doris P.; Altrock, Philipp M.; et al. NATURE  Volume: 514   Issue: 7520   Pages: 54-+
  • Dissecting tumour heterogeneity in flies: genetic basis of interclonal oncogenic cooperation. Ohsawa, Shizue; Takemoto, Daisaku; Igaki, Tatsushi JOURNAL OF BIOCHEMISTRY  Volume: 156   Issue: 3   Pages: 129-136
  • Tumour heterogeneity and the evolution of polyclonal drug resistance. Burrell, Rebecca A.; Swanton, Charles
    MOLECULAR ONCOLOGY  Volume: 8   Issue: 6   Pages: 1095-1111
  • Game theory in the death galaxy: interaction of cancer and stromal cells in tumour microenvironment. Wu, Amy; Liao, David; Tlsty, Thea D.; et al. INTERFACE FOCUS  Volume: 4   Issue: 4 Special Issue: SI Article Number: 20140028
  • The ecology of cancer from an evolutionary game theory perspective. Pacheco, Jorge M.; Santos, Francisco C.; Dingli, David. INTERFACE FOCUS  Volume: 4   Issue: 4 Special Issue: SI Article Number: 20140019
  • Beyond evolution: game theory and the progression of cancer. Austin, Robert
    INTERFACE FOCUS  Volume: 4   Issue: 4   Special Issue: SI Article Number: 20140044   
  • Evolution of acquired resistance to anti-cancer therapy. Foo, Jasmine; Michor, Franziska. JOURNAL OF THEORETICAL BIOLOGY  355:10-20 
  • Using Systems Biology to Understand Cancer as an Evolutionary Process. Pepper JW et al. Journal of Evolutionary Medicine 2: Article ID 235678
  • Can a minimal replicatong construct be identified as the embodiment of cancer? Ricard V. Sole et al. BioEssays 36:503-512.
  • Cancer Evolution Is Associated with Pervasive Positive Selection on Globally Expressed Genes. By: Sheli L. Ostrow, Ruth Barshir, James DeGregori, Esti Yeger-Lotem, Ruth Hershberg. PLOS Genetics Volume 10 | Issue 3 | e1004239
  • Combating Evolution to Fight Disease
    By: Rosenberg, Susan M.; Queitsch, Christine
    SCIENCE  Volume: 343   Issue: 6175   Pages: 1088-1089  
  • Cancer evolution: the final frontier of precision medicine?
    By: Swanton, Charles
    ANNALS OF ONCOLOGY  Volume: 25   Issue: 3   Pages: 549-551 
  • Complex adaptive therapeutic strategy (CATS) for cancer
    By: Cho, Yong Woo; Kim, Sang Yoon; Kwon, Ick Chan; et al.
    JOURNAL OF CONTROLLED RELEASE  Volume: 175   Pages: 43-47 
  • Tumor Evolution in Response to Chemotherapy: Phenotype versus Genotype
    By: Navin, Nicholas E.
    CELL REPORTS  Volume: 6   Issue: 3   Pages: 417-419  
  • Inference of Tumor Evolution during Chemotherapy by Computational Modeling and In Situ Analysis of Genetic and Phenotypic Cellular Diversity
    By: Almendro, Vanessa; Cheng, Yu-Kang; Randles, Amanda; et al.
    CELL REPORTS  Volume: 6   Issue: 3   Pages: 514-527  
  • Evolutionary dynamics of the Warburg effect: Glycolysis as a collective action problem among cancer cells
    By: Archetti, Marco
    JOURNAL OF THEORETICAL BIOLOGY  Volume: 341   Pages: 1-8  
  • Temporal and Spatial Evolution of Somatic Chromosomal Alterations: A Case-Cohort Study of Barrett's Esophagus
    By: Li, Xiaohong; Galipeau, Patricia C.; Paulson, Thomas G.; et al.
    CANCER PREVENTION RESEARCH  Volume: 7   Issue: 1   Pages: 114-127  
2013
  • Aktipis, C. Athena; Boddy, Amy M.; Gatenby, Robert A.; et al. Life history trade-offs in cancer evolution. NATURE REVIEWS CANCER  Volume: 13   Issue: 12   Pages: 883-892  
  • Diego, David; Calvo, Gabriel F.; Perez-Garcia, Victor M. 2013. Modeling the connection between primary and metastatic tumors.  JOURNAL OF MATHEMATICAL BIOLOGY  Volume: 67   Issue: 3   Pages: 657-692
  • Werner, Benjamin; Dingli, David; Traulsen, Arne. 2013. A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissues.  JOURNAL OF THE ROYAL SOCIETY INTERFACE  Volume: 10   Issue: 85     Article Number: 20130349
  • Gallaher, Jill; Anderson, Alexander R. A. 2013. Evolution of intratumoral phenotypic heterogeneity: the role of trait inheritance. INTERFACE FOCUS  Volume: 3   Issue: 4   Special Issue: SI  
  • Foo, Jasmine; Leder, Kevin. 2013. DYNAMICS OF CANCER RECURRENCE. ANNALS OF APPLIED PROBABILITY  Volume: 23   Issue: 4   Pages: 1437-1468 
  • Humphries, Adam; Cereser, Biancastella; Gay, Laura J.; et al. 2013.  Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution.  PNAS  Volume: 110   Issue: 27   Pages: E2490-E2499
  •  Newburger, Daniel E.; Kashef-Haghighi, Dorna; Weng, Ziming; et al.. 2013.  Genome evolution during progression to breast cancer. GENOME RESEARCH  Volume: 23   Issue: 7   Pages: 1097-1108
  • Barcellos-Hoff, Mary Helen; Lyden, David; Wang, Timothy C.  The evolution of the cancer niche during multistage carcinogenesis. NATURE REVIEWS CANCER  Volume: 13   Issue: 7   Pages: 511-518
  • Sefah, Kwame; Bae, Kyung-Mi; Phillips, Joseph A.; et al. 2013. Cell-based selection provides novel molecular probes for cancer stem cells,  INTERNATIONAL JOURNAL OF CANCER  132: 2578-2588
  • Scott, Jacob G.; Basanta, David; Anderson, Alexander R. A.; et al. 2013. A mathematical model of tumour self-seeding reveals secondary metastatic deposits as drivers of primary tumour growth. JOURNAL OF THE ROYAL SOCIETY INTERFACE  10: 20130011
  • DeGregori, J. 2013. Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age? ONCOGENE  32: 1869-1875   
  • Taylor, Tiffany B.; Johnson, Louise J.; Jackson, Robert W.; et al. 2013. First steps in experimental cancer evolution . EVOLUTIONARY APPLICATIONS  6: 535-548  
  • Ahmed, Muhammed; Li, Long-Cheng. 2013. Adaptation and clonal selection models of castration-resistant prostate cancer: Current perspective. INTERNATIONAL JOURNAL OF UROLOGY  20: 362-371
  • Davila, Alfonso F.; Zamorano, Pedro. 2013. Mitochondria and the evolutionary roots of cancer. PHYSICAL BIOLOGY  10: 026008
  • Sottoriva, Andrea; Spiteri, Inmaculada; Piccirillo, Sara G. M.; et al. 2013. Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA  110: 4009-4014
  • Calderwood, Stuart K. 2013. Tumor Heterogeneity, Clonal Evolution, and Therapy Resistance: An Opportunity for Multitargeting Therapy. DISCOVERY MEDICINE  82: 188-194
  • Lam, P.; Khan, G.; Stripecke, R.; et al. 2013. The innovative evolution of cancer gene and cellular therapies. CANCER GENE THERAPY  20: 141-149
  • Muhammed Murtaza, et al. 2013. Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature doi:10.1038/nature12065
  • Lorz, Alexander; Lorenzi, Tommaso; Hochberg, Michael E.; et al.
    2013. Populational adaptive evolution, chemotherapeutic resistance and multiple anti-cancer tehrapies. ESAIM-MATHEMATICAL MODELLING AND NUMERICAL ANALYSIS-MODELISATION MATHEMATIQUE ET ANALYSE NUMERIQUE  47: 377-403
  • Puente, Xose S.; Lopez-Otin, Carlos. 2013. The evolutionary biography of chronic lymphocytic leukemia. NATURE GENETICS   45: 229-231
  • Castellarin, Mauro; Milne, Katy; Zeng, Thomas; et al. 2013. Clonal evolution of high-grade serous ovarian carcinoma from primary to recurrent disease. JOURNAL OF PATHOLOGY 229: 515-524
  • Aparicio, Samuel; Caldas, Carlos. 2013. The Implications of Clonal Genome Evolution for Cancer Medicine. NEW ENGLAND JOURNAL OF MEDICINE  368: 842-851
  • Landau, Dan A.; Carter, Scott L.; Stojanov, Petar; et al. 2013. Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia. CELL  152: 714-726
  • Tomasetti, Cristian; Vogelstein, Bert; Parmigiani, Giovanni. 2013. Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110: 1999-2004
  • Durrett, Rick. 2013. ANNALS OF APPLIED PROBABILITY  23: 230-250
  • Kreso, Antonija; O'Brien, Catherine A.; van Galen, Peter; et al. 2013. Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer SCIENCE  6119: 543-548 
  • Ignacio Tello, J. 2013. ON A MATHEMATICAL MODEL OF TUMOR GROWTH BASED ON CANCER STEM CELLS  MATHEMATICAL BIOSCIENCES AND ENGINEERING  1: 263-278
  • Flossbach, Lucia; Holzmann, Karlheinz; Mattfeldt, Torsten; et al. 2013. High-resolution genomic profiling reveals clonal evolution and competition in gastrointestinal marginal zone B-cell lymphoma and its large cell variant INTERNATIONAL JOURNAL OF CANCER   3: E116-E127
  • Jan, M.; Majeti, R. 2013. Clonal evolution of acute leukemia genomes ONCOGENE   2: 135-140
  • Ujvari, Beata; Pearse, Anne-Maree; Peck, Sarah; et al. 2013. Evolution of a contagious cancer: epigenetic variation in Devil Facial Tumour Disease PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES   1750, Article Number: 20121720 
  • Atwood, Scott X.; Chang, Anne Lynn S.; Oro, Anthony E. 2013. Hedgehog pathway inhibition and the race against tumor evolution
    JOURNAL OF CELL BIOLOGY  Special Issue: SI   Pages: 45-49
  • Thomas, Frederic; Fisher, Daniel; Fort, Philippe; et al. 2013 Applying ecological and evolutionary theory to cancer: a long and winding road  EVOLUTIONARY APPLICATIONS   Special Issue: SI   Pages: 1-10
  • Nunney, Leonard. 2013. The real war on cancer: the evolutionary dynamics of cancer suppression EVOLUTIONARY APPLICATIONS  Special Issue: SI   Pages: 11-19 
  • Datta, Ruchira S.; Gutteridge, Alice; Swanton, Charles; et al. 2013. Modelling the evolution of genetic instability during tumour progression EVOLUTIONARY APPLICATIONS   Special Issue: SI   Pages: 20-33 
  • Alfarouk, Khalid O.; Ibrahim, Muntaser E.; Gatenby, Robert A.; et al. 2013. Riparian ecosystems in human cancers EVOLUTIONARY APPLICATIONS Special Issue: SI   Pages: 46-53
  • Ewald, Paul W.; Ewald, Holly A. Swain. 2013. Toward a general evolutionary theory of oncogenesis EVOLUTIONARY APPLICATIONS  Special Issue: SI   Pages: 70-81
  • Daoust, Simon P.; Fahrig, Lenore; Martin, Amanda E.; et al. 2013. From forest and agro-ecosystems to the microecosystems of the human body: what can landscape ecology tell us about tumor growth, metastasis, and treatment options? EVOLUTIONARY APPLICATIONS    Special Issue: SI   Pages: 82-91 
  • Sprouffske, Kathleen; Aktipis, C. Athena; Radich, Jerald P.; et al. 2013. An evolutionary explanation for the presence of cancer nonstem cells in neoplasms EVOLUTIONARY APPLICATIONS    Special Issue: SI   Pages: 92-101
  • Greaves, Mel. 2013. Cancer stem cells as 'units of selection' EVOLUTIONARY APPLICATIONS Special Issue: SI   Pages: 102-108
  • Roche, Benjamin; Sprouffske, Kathleen; Hbid, Hassan; et al. 2013. Peto's paradox revisited: theoretical evolutionary dynamics of cancer in wild populations EVOLUTIONARY APPLICATIONS  Special Issue: SI   Pages: 109-116
  • Hochberg, Michael E.; Thomas, Frederic; Assenat, Eric; et al. 2013. Preventive Evolutionary Medicine of Cancers EVOLUTIONARY APPLICATIONS   Special Issue: SI   Pages: 134-143
  • Aktipis, C. Athena; Nesse, Randolph M. 2013. Evolutionary foundations for cancer biology EVOLUTIONARY APPLICATIONS  Special Issue: SI   Pages: 144-159
  • Silva, Ariosto S.; Kam, Yoonseok; Khin, Zayar P.; et al. 2013.Evolutionary Approaches to Prolong Progression-Free Survival in Breast Cancer CANCER RESEARCH  24: 6362-6370
2012
  • Schuh A, Becq J, Humphray S et al. 2012. Monitoring chronic lymphocytic leukemia progression by whole genome sequencing reveals heterogeneous clonal evolution patterns BLOOD  120: 4191-4196
  • Orlando PA, Gatenby RA, Brown JS. 2012. Cancer treatment as a game: integrating evolutionary game theory into the optimal control of chemotherapy PHYSICAL BIOLOGY  9: 065007
  • Danesh K, Durrett R, Havrilesky LJ et al. 2012. A branching process model of ovarian cancer JOURNAL OF THEORETICAL BIOLOGY   314: 10-15
  • Sorace R, Komarova NL. 2012. Accumulation of neutral mutations in growing cell colonies with competition JOURNAL OF THEORETICAL BIOLOGY  314: 84-94
  • Flossbach L, Holzmann K, Mattfeldt T et al. 2012 High-resolution genomic profiling reveals clonal evolution and competition in gastrointestinal marginal zone B-cell lymphoma and its large cell variant INTERNATIONAL JOURNAL OF CANCER 132: E116-E127
  • Hochberg ME, Thomas F, Assenat E, Hibner U. 2012. Preventive Evolutionary Medicine of Cancers. Evolutionary Applications. doi:10.1111/eva.12033
  • Sprouffske K, Aktipis CA, Radich JP, Carroll M, Nedelcu AM, Maley CC.  2012. An evolutionary explanation for the presence of cancer nonstem cells in neoplasms. Evolutionary Applications doi:10.1111/eva.12030
  • Roche B, Sprouffske K, Hbid H, Misse D, Thomas F. 2012. Peto's paradox revisited: theoretical evolutionary dynamics of cancer in wild populations. Evolutionary Applications doi:10.1111/eva.12025
  • Datta RS, Gutteridge A, Swanton C, Maley CC, Graham TA. 2012. Modelling teh evolution of genetic instability during tumor progression. Evolutionary Applicationsdoi:10.1111/eva.12024
  • Ewald PW and Ewald HAS. 2012. Toward a general evolutionary rheory of oncogenesis. Evolutionary Applications doi:10.1111/eva.12023
  • Thomas F, Fisher D, et al. 2012. Applying ecological and evolutionary theory to cancer: a long and winding road. Evolutionary Applications  doi:10.1111/eva.12021
  • Nunney L. 2012. The real war on cancer: the evolutionary dynamics of cancer suppression. Evolutiinary Applications. doi:10.1111/eva.12018
  • Greaves, M. 2012. Cancer stem cells as 'units of selection'. Evolutionary Applications. doi:10.1111/eva.1201
  • Swanton, C. 2012. Intratumor Heterogeneity: Evolution through Space and Time. CANCER RESEARCH  72: 4875-4882
  • Nagy, JD.; Armbruster, D. 2012 EVOLUTION OF UNCONTROLLED PROLIFERATION AND THE ANGIOGENIC SWITCH IN CANCER. MATHEMATICAL BIOSCIENCES AND ENGINEERING  9: 843-876  
  • Pepper, JW. 2012. Drugs that target pathogen public goods are robust against evolved drug resistance EVOLUTIONARY APPLICATIONS 5: 757-761
  • Stearns, Stephen C. 2012. Evolutionary medicine: its scope, interest and potential. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES  279: 4305-4321
  • Lucy R. Yates and Peter J. Campbell. 2012. Evolution of the cancer genome. Nature Reviews Genetics 13: 795-806
  • Sprouffske K, LMF Merlo, PJ Gerrish, CC Maley, PD Sniegowski. 2012. Cancer in light of experimental evolution. Current Biology: 22(17): R762-71
  • Morange, Michel. 2012. What history tells us XXVIII. What is really new in the current evolutionary theory of cancer? JOURNAL OF BIOSCIENCES  37(4): 609-612
  • Alvarado, Alejandro Sanchez. 2012. Cellular Hyperproliferation and Cancer as Evolutionary Variables CURRENT BIOLOGY  22(17): R772-R778
  • Frank, Steven A.; Rosner, Marsha Rich. 2012. Nonheritable Cellular Variability Accelerates the Evolutionary Processes of Cancer PLOS BIOLOGY  10(4): e1001296  
  • Powathil, Gibin G.; Gordon, Kirsty E.; Hill, Lydia A.; et al. 2012. Modelling the effects of cell-cycle heterogeneity on the response of a solid tumour to chemotherapy: Biological insights from a hybrid multiscale cellular automaton model JOURNAL OF THEORETICAL BIOLOGY  308: 1-19
  • Bahlis, Nizar J. 2012. Darwinian evolution and tiding clones in multiple myeloma. BLOOD  120(5): 927-928  
  • Mitrus, Iwona et al. 2012. Evolving models of tumor origin and progression. TUMOR BIOLOGY  33(4): 911-917
  • Welch, John S.; Ley, Timothy J.; Link, Daniel C.; et al. 2012. The Origin and Evolution of Mutations in Acute Myeloid Leukemia. CELL 150(2): 264-278 
  • Driessens, G; Beck, B; Caauwe, A; Simons, BD; Blanpain, C. 2012.
    Defining the mode of tumour growth by clonal analysis. NATURE  488(7412): 527- 
  • Powathil GG, Gordon K, Hill, Lydia A et al. 2012. Modelling the effects of cell-cycle heterogeneity on the response of a solid tumour to chemotherapy: Biological insights from a hybrid multiscale cellular automaton model. JOURNAL OF THEORETICAL BIOLOGY  308: 1-19
  • Keats JJ, Chesi M, Egan JB et al. 2012. Clonal competition with alternating dominance in multiple myeloma. BLOOD  120(5): 1067-1076  
  • Vincent M. 2012. Cancer: A de-repression of a default survival program common to all cells? BIOESSAYS  34(1): 72-82
  • Moore A. 2012. TOR: The ancient link between cancer and ageing?
    BIOESSAYS  34(6): 443-444
  • Thomas F, Elguero E, Brodeur J, Roche B, Misse  D and Raymond M. 2012. Malignancies and High Birth Weight in Human: Which Cancers Could Result from Antagonistic Pleiotropy? Journal of Evolutionary Medicine Vol. 1 Article ID Q120502, doi:10.4303/jem/Q120502
  • Knauss S and Klein A. 2012. From aneuploidy to cancer: The evolution of a new species? JOURNAL OF BIOSCIENCES  37(2): 211-220
  • Beckman RA, Schemmann GS, Yeang C-H. 2012. Impact of genetic dynamics and singel-cell heterogeneity on development of nonstandard personalized medicine strategies for cancer. PNAS Early Edition doi/10.1073/pnas.1203559109
  • Yang, Chao; Shi, Xiaoyun; Huang, Yun; et al. 2012. Rapid proliferation of daughter cells lacking particular chromosomes due to multipolar mitosis promotes clonal evolution in colorectal cancer cells. CELL CYCLE  11(14): 2650-2659   
  • Bendall, Sean C.; Nolan, Garry P. 2012. From single cells to deep phenotypes in cancer. NATURE BIOTECHNOLOGY  30(7): 639-647
  • Braggio, E.; Kay, N. E.; VanWier, S.; et al. 2012. Longitudinal genome-wide analysis of patients with chronic lymphocytic leukemia reveals complex evolution of clonal architecture at disease progression and at the time of relapse. LEUKEMIA 26(7): 1698-1701 
  • Gilbertson RJ and Graham TA. 2012. Cancer: Resolving the stem-cell debate. Nature doi:10.1038/nature11480
  • Driessens G et al. 2012. Defining the mode of tumor growth by clonal analysis. Nature doi:10.1038/nature11344
  • Liu Q.; Liu Z. 2012. Malignancy through cooperation: an evolutionary game theory approach. CELL PROLIFERATION  Volume: 45   Issue: 4   Pages: 365-377
  • Gillies Robert J.; Verduzco Daniel; Gatenby Robert A. Evolutionary dynamics of carcinogenesis and why targeted therapy does not work. NATURE REVIEWS CANCER  Volume: 12   Issue: 7   Pages: 487-493
  • Bock Christoph; Lengauer Thomas. 2012. Managing drug resistance in cancer: lessons from HIV therapy. NATURE REVIEWS CANCER  Volume: 12   Issue: 7   Pages: 494-501
  • Iacobuzio-Donahue Christine A. 2012. Genetic evolution of pancreatic cancer: lessons learnt from the pancreatic cancer genome sequencing project. GUT  Volume: 61   Issue: 7   Pages: 1085-1094
  • Diaz Luis A. Jr.; Williams Richard T.; Wu Jian; et al. 2012. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. NATURE  Volume: 486   Issue: 7404   Pages: 537-540
  • Shah Sohrab P.; Roth Andrew; Goya Rodrigo; et al. 2012. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. NATURE  Volume: 486   Issue: 7403   Pages: 395-399
  • Bozic Ivana; Allen Benjamin; Nowak Martin A. 2012. Dynamics of targeted cancer therapy. TRENDS IN MOLECULAR MEDICINE  Volume: 18   Issue: 6   Pages: 311-316
  • Antolin, MF; Jenkins, KP ; Bergstrom, CT ; Crespi, BJ; De, S ; Hancock, A ; Hanley, KA ; Meagher, TR; Moreno-Estrada, A ; Nesse, RM; Omenn, GS; Stearns, SC. 2012. EVOLUTION AND MEDICINE IN UNDERGRADUATE EDUCATION: A PRESCRIPTION FOR ALL BIOLOGY STUDENTS. EVOLUTION  Volume: 66   Issue: 6   Pages: 1991-2006 
  • Knauss Samuel; Klein Andreas. 2012. From aneuploidy to cancer: The evolution of a new species? JOURNAL OF BIOSCIENCES  Volume: 37   Issue: 2   Pages: 211-220
  • Nik-Zainal Serena; Van Loo Peter; Wedge David C.; et al. 2012. The Life History of 21 Breast Cancers. CELL  Volume: 149   Issue: 5  
  • McGuire Terence F.; Sajithlal Gangadharan B.; Lu Jie; et al. 2012. In Vivo Evolution of Tumor-Derived Endothelial Cells. PLOS ONE  Volume: 7   Issue: 5     Article Number: e37138 
  • Nesse Randolph M.; Ganten Detlev; Gregory T. Ryan; et al. 2012. Evolutionary molecular medicine.  JOURNAL OF MOLECULAR MEDICINE  Volume: 90 Issue: 5 
  • Caldas Carlos. 2012. Cancer sequencing unravels clonal evolution. NATURE BIOTECHNOLOGY  Volume: 30   Issue: 5   Pages: 408-410
  • DeGregory J. 2012. Challenging the axiom: does the ocurence of oncogenic mutations truly limit cancer development with age? Oncogene. doi:10.1038/onc.2012.281
  • Brosnan JA, Iacobuzio-Donahue CA. 2012. A new branch on the tree: Next-generation sequencing in the study of cancer evolution. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY 23( 2):237-242
  • Frank SA and Rosner MR. 2012. Nonheritable Cellular Variability Accelerates the Evolutionary Processes of Cancer. PLOS BIOLOGY  10(4): e1001296
  • Bredberg A. 2012. Peto's paradox and cancer: a response to Caulin and Maley. TRENDS IN ECOLOGY & EVOLUTION  27(5):254-255
  • Marusyk A, Almendro V, Polyak K. 2012. Intra-tumour heterogeneity: a looking glass for cancer? NATURE REVIEWS CANCER  12(5):323-334  
  • Jacobs KB et al. 2012. Detectable clonal mosaicism and its relationship to aging and cancer. Nature Genetics 44: 651-658
  • Laurie CC et al. 2012. Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nature Genetics 44: 642-650
  • Shibata D. 2012. Heterogeneity and Tumor History. Science 336:304-305.
  • Shah SP et al. 2012. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature (in press)
  • Nc CKY, Cooke SL et al. 2012. The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer. J of Pathology 226: 703-712.
  • Caldwell ME, DeNicola Gm et al. 2012. Cellular features of senescence during the evolution of human and murine ductal pancreatic cancer. Oncogene 31:1599-1608.
  • Hatzikirou H, Basanta D, et al. 2012. 'Go or Grow': the key to the emergence of invasion in tumor progression? Math Med Biol. 29:49-65.
  • Pienta KJ, Camacho DF. Disrupting the networks of cancer. Clin Cancer Res PMID:
     22442061
  • Ewald PW, Swain Ewald HA. 2012. Infection, mutation and cancer evolution. J Mol Med 90(5):535-41. PMID:22476248
  • Gerlinger M et al. 2012. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. New England Journal of Medicine 366:883-892.
  • Delitala M, Lorenzi T. 2012. A mathematical model for the dynamics of cancer hepatocytes under therapeutic actions. J Theoretical Biology 297:88-102.
  • Walter MJ et al. 2012. Clonal architecture of secondary acute myeloid leukemia. New England Journal of Medicine 366:1090-1098.
  • Belov K. 2012. Contagious cancer: Lessons from the devil and the dog. Bioessays 34:285-292.
  • Hirsch D et al. 2012. A new whole genome apmplification method for studying clonal evolution patterns in malignant colorectal polyps. Genes Chromosomes & Cancer 51:490-500.
  • Nguyen LV et al. 2012. Cancer stem cells: an evolving concept. Nature Reviews Cancer 12:133-143.
  • Magee JA, Piskounova E, Morrison SJ. 2012. Cancer Stem Cells: Impact, heterogeneity, and uncertainty. Cancer Cell 21:283-296.
  • Casanovas O. 2012. Limitations of therapies exposed. Nature 484:44-46.
  • Billaud M, Santoro M. 2011. IS Co-option a prevailing mechanism during cancer progression? Cancer Research 71(21): 6572-6575.
  • Wu X, Northcott PA, et al. Clonal selection drives genetic divergence of metastatic medulloblastoma. Nature 482: 529- (doi:10.1038/nature10825)
  • Dunn B. Solving an age-old problem. Is cancer ancient, or is it largely a product of modern times? Nature 483. 1 March 2012. S2-S6.
  • Podlaha O, Riester M, De S, Michor F. 2012. Evolution of the cancer genome. Trends Genet. 28:155-163.
  • Basanta D, Gatenby RA, Anderson AR. 2012. Exploiting evolution to treat drug resistance: Combination therapy and the double bind. Mol Pharm. 9:914-921.
  • Martin NK, Robey IF, Gaffney EA, Gillies RJ, Gatenby RA, Maini PK. Predicting the safety and efficacy of buffer therapy to raise tumour pH: an integrative modelling study.Br J Cancer. 2012 Mar 1. doi: 10.1038/bjc.2012.58. 
  • Kam Y, Rejniak KA, Anderson AR. Cellular modeling of cancer invasion: integration of in silico and in vitro approaches. J Cell Physiol. 2012 Feb;227(2):431-8. doi: 10.1002/jcp.22766. Review.
  • Rejniak KA, Anderson AR. 2012. State of the art in computational modelling of cancer. Math Med Biol 29:1-2.
  • Aktipis CA, Maley CC, Pepper JW. 2012. Dispersal evolution in neoplasms: The role of disregulated metabolism in the evolution of cell motility. Cancer Prevention Research 5:266-275.
  • Basanta D, Scott JG, Fishman MN, Ayala G, Hayward SW, Anderson AR. 2012. Investigating prostate cancer tumour-stroma interactions: clinical and biological insights from an evolutionary game. Br J Cancer 106(1):174-181
  • Haeno H, Gonen M, Davis MB, Herman JM, Iacobuzio-Donahue CA, Michor F. 2012.  Computational modeling of pancreatic cancer reveals kinetics of metastasis suggesting optimum treatment strategies. Cell 148(1-2):362-375
2011
2010